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Biomaterial-Based Nanocomposite for Osteogenic Repurposing of Doxycycline

BACKGROUND: Besides its antimicrobial action, doxycycline (DX) has lately been repurposed as a small-molecule drug for osteogenic purposes. However, osteogenic DX application is impeded by its dose-dependent cytotoxicity. Further, high-dose DX impairs cell differentiation and mineralization. PURPOSE...

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Detalles Bibliográficos
Autores principales:	El-Habashy, Salma, Eltaher, Hoda, Gaballah, Ahmed, Mehanna, Radwa, El-Kamel, Amal H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887185/ https://www.ncbi.nlm.nih.gov/pubmed/33603371 http://dx.doi.org/10.2147/IJN.S298297

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