Asymmetric opening of the homopentameric 5-HT(3A) serotonin receptor in lipid bilayers

Pentameric ligand-gated ion channels (pLGICs) of the Cys-loop receptor family are key players in fast signal transduction throughout the nervous system. They have been shown to be modulated by the lipid environment, however the underlying mechanism is not well understood. We report three structures...

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Detalles Bibliográficos
Autores principales: Zhang, Yingyi, Dijkman, Patricia M., Zou, Rongfeng, Zandl-Lang, Martina, Sanchez, Ricardo M., Eckhardt-Strelau, Luise, Köfeler, Harald, Vogel, Horst, Yuan, Shuguang, Kudryashev, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887223/
https://www.ncbi.nlm.nih.gov/pubmed/33594077
http://dx.doi.org/10.1038/s41467-021-21016-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887223/
https://www.ncbi.nlm.nih.gov/pubmed/33594077
http://dx.doi.org/10.1038/s41467-021-21016-7

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