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Asymmetric opening of the homopentameric 5-HT(3A) serotonin receptor in lipid bilayers
Pentameric ligand-gated ion channels (pLGICs) of the Cys-loop receptor family are key players in fast signal transduction throughout the nervous system. They have been shown to be modulated by the lipid environment, however the underlying mechanism is not well understood. We report three structures...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887223/ https://www.ncbi.nlm.nih.gov/pubmed/33594077 http://dx.doi.org/10.1038/s41467-021-21016-7 |