Cargando…

ABCC6 deficiency promotes dyslipidemia and atherosclerosis

ABCC6 deficiency promotes ectopic calcification; however, circumstantial evidence suggested that ABCC6 may also influence atherosclerosis. The present study addressed the role of ABCC6 in atherosclerosis using Ldlr(−/−) mice and pseudoxanthoma elasticum (PXE) patients. Mice lacking the Abcc6 and Ldl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brampton, Christopher, Pomozi, Viola, Chen, Li-Hsieh, Apana, Ailea, McCurdy, Sara, Zoll, Janna, Boisvert, William A., Lambert, Gilles, Henrion, Daniel, Blanchard, Simon, Kuo, Sheree, Leftheriotis, Georges, Martin, Ludovic, Le Saux, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887252/ https://www.ncbi.nlm.nih.gov/pubmed/33594095 http://dx.doi.org/10.1038/s41598-021-82966-y

Ejemplares similares

Analysis of Pseudoxanthoma Elasticum-Causing Missense Mutants of ABCC6 in vivo; Pharmacological Correction of the Mislocalized Proteins
por: Pomozi, Viola, et al.
Publicado: (2013)

ABCC6, Pyrophosphate and Ectopic Calcification: Therapeutic Solutions
por: Shimada, Briana K., et al.
Publicado: (2021)

The molecular and physiological roles of ABCC6: more than meets the eye
por: Le Saux, Olivier, et al.
Publicado: (2012)

Pseudoxanthoma Elasticum: Cardiac Findings in Patients and Abcc6-Deficient Mouse Model
por: Prunier, Fabrice, et al.
Publicado: (2013)

Expression and In Vivo Rescue of Human ABCC6 Disease-Causing Mutants in Mouse Liver
por: Le Saux, Olivier, et al.
Publicado: (2011)

Transcriptional regulation of the ABCC6 gene and the background of impaired function of missense disease-causing mutations
por: Arányi, Tamás, et al.
Publicado: (2013)

Is ABCC6 a genuine mitochondrial protein?
por: Ferré, Marc, et al.
Publicado: (2013)

The ABCC6 Transporter: A New Player in Biomineralization
por: Favre, Guillaume, et al.
Publicado: (2017)

ABCC6 deficiency and bone loss: A double benefit of etidronate for patient presenting with pseudoxanthoma elasticum?
por: Kauffenstein, Gilles, et al.
Publicado: (2022)

The vascular phenotype in Pseudoxanthoma elasticum and related disorders: contribution of a genetic disease to the understanding of vascular calcification
por: Lefthériotis, Georges, et al.
Publicado: (2013)

The Contribution of Arterial Calcification to Peripheral Arterial Disease in Pseudoxanthoma Elasticum
por: Leftheriotis, Georges, et al.
Publicado: (2014)

Plasma Level of Pyrophosphate Is Low in Pseudoxanthoma Elasticum Owing to Mutations in the ABCC6 Gene, but It Does Not Correlate with ABCC6 Genotype
por: Kozák, Eszter, et al.
Publicado: (2023)

Atherosclerosis Calcification: Focus on Lipoproteins
por: Neels, Jaap G., et al.
Publicado: (2023)

Zebrafish Models for Dyslipidemia and Atherosclerosis Research
por: Schlegel, Amnon
Publicado: (2016)

Relationships between Plasma Pyrophosphate, Vascular Calcification and Clinical Severity in Patients Affected by Pseudoxanthoma Elasticum
por: Leftheriotis, Georges, et al.
Publicado: (2022)

Evidence of Cardiovascular Calcification and Fibrosis in Pseudoxanthoma Elasticum Mouse Models Subjected to DOCA-Salt Hypertension
por: Omarjee, Loukman, et al.
Publicado: (2019)

Defective Fas Expression on Bone Marrow Derived Cells Alters Atherosclerotic Plaque Morphology in Hyperlipidemic Mice
por: Kubo, Nobuhiko, et al.
Publicado: (2015)

New insight into dyslipidemia‐induced cellular senescence in atherosclerosis
por: Xiang, Qunyan, et al.
Publicado: (2022)

Lysosomal acid lipase deficiency: A rare inherited dyslipidemia but potential ubiquitous factor in the development of atherosclerosis and fatty liver disease
por: Besler, Katrina J., et al.
Publicado: (2022)

ATP-Binding Cassette Protein ABCC10 Deficiency Prevents Diet-Induced Obesity but Not Atherosclerosis in Mice
por: Otaibi, Abeer Al, et al.
Publicado: (2022)

Atherosclerosis, Dyslipidemia, and Inflammation: The Significant Role of Polyunsaturated Fatty Acids
por: Dessì, Mariarita, et al.
Publicado: (2013)

TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis
por: Zysset, Daniel, et al.
Publicado: (2016)

In Search for Genes Related to Atherosclerosis and Dyslipidemia Using Animal Models
por: Poznyak, Anastasia V., et al.
Publicado: (2020)

Etidronate prevents dystrophic cardiac calcification by inhibiting macrophage aggregation
por: Bauer, Carolin, et al.
Publicado: (2018)

Roles of ABCC1 and ABCC4 in Proliferation and Migration of Breast Cancer Cell Lines
por: Low, Floren G., et al.
Publicado: (2020)

Association of atherosclerosis with dyslipidemia and co-morbid conditions: A descriptive study
por: Garg, Ravinder, et al.
Publicado: (2015)

The Correlation of Dyslipidemia with the Extent of Coronary Artery Disease in the Multiethnic Study of Atherosclerosis
por: Abd alamir, Moshrik, et al.
Publicado: (2018)

Monocyte DPP4 Expression in Human Atherosclerosis Is Associated With Obesity and Dyslipidemia
por: Rao, Xiaoquan, et al.
Publicado: (2018)

Dyslipidemia, Diabetes and Atherosclerosis: Role of Inflammation and ROS-Redox-Sensitive Factors
por: Hasheminasabgorji, Elham, et al.
Publicado: (2021)

ABCC9 Is Downregulated and Prone to Microsatellite Instability on ABCC9tetra in Canine Breast Cancer
por: Hao, Pan, et al.
Publicado: (2022)

Abnormally high failure rate for femoral angioplasty in patients with pseudoxanthoma elasticum
por: Ammi, Myriam, et al.
Publicado: (2015)

Clinicopathological Impact of ABCC1/MRP1 and ABCC4/MRP4 in Epithelial Ovarian Carcinoma
por: Bagnoli, Marina, et al.
Publicado: (2013)

The TBK1/IKKε inhibitor amlexanox improves dyslipidemia and prevents atherosclerosis
por: Zhao, Peng, et al.
Publicado: (2022)

Acute Ischemic Stroke Caused by Intracranial Atherosclerosis Associated With Lorlatinib-Induced Dyslipidemia
por: Hwang, Jaechun, et al.
Publicado: (2023)

Haxe game development essentials: create games on multiple platforms from a single codebase using Haxe and the HaxeFlixel engine
por: McCurdy, Jeremy
Publicado: (2015)

THE INFLUENCE OF THYROIDECTOMY ON ALIMENTARY GLYCOSURIA
por: McCurdy, John
Publicado: (1909)

The rise and fall of the Synthetic: The mediatization of Canada's oil sands
por: McCurdy, Patrick
Publicado: (2023)

Three novel ABCC5 splice variants in human retina and their role as regulators of ABCC5 gene expression
por: Stojic, Jelena, et al.
Publicado: (2007)

Apolipoprotein E4 Exaggerates Diabetic Dyslipidemia and Atherosclerosis in Mice Lacking the LDL Receptor
por: Johnson, Lance A., et al.
Publicado: (2011)

Nobiletin Attenuates VLDL Overproduction, Dyslipidemia, and Atherosclerosis in Mice With Diet-Induced Insulin Resistance
por: Mulvihill, Erin E., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_9uncejuobem7likv8ihra4a6vi