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Depot medroxyprogesterone acetate (DMPA) enhances susceptibility and increases the window of vulnerability to HIV-1 in humanized mice

The progestin-based hormonal contraceptive Depot Medroxyprogesterone Acetate (DMPA) is widely used in sub-Saharan Africa, where HIV-1 is endemic. Meta-analyses have shown that women using DMPA are 40% more likely than women not using hormonal contraceptives to acquire Human Immunodeficiency Virus (H...

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Detalles Bibliográficos
Autores principales: Wessels, Jocelyn M., Nguyen, Philip V., Vitali, Danielle, Mueller, Kristen, Vahedi, Fatemeh, Felker, Allison M., Dupont, Haley A., Bagri, Puja, Verschoor, Chris P., Deshiere, Alexandre, Mazzulli, Tony, Tremblay, Michel J., Ashkar, Ali A., Kaushic, Charu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887257/
https://www.ncbi.nlm.nih.gov/pubmed/33594113
http://dx.doi.org/10.1038/s41598-021-83242-9