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SIRT1 alleviates hepatic ischemia-reperfusion injury via the miR-182-mediated XBP1/NLRP3 pathway

The hepatoprotection of histone deacetylase sirtuin 1 (SIRT1) has been identified to attenuate ischemia-reperfusion (IR)-triggered inflammation and liver damage. This study was performed to characterize the function of SIRT1 in hepatic IR injury. In in vivo assays on liver-specific knockout mice of...

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Detalles Bibliográficos
Autores principales:	Li, Fengwei, Zhang, Lei, Xue, Hui, Xuan, Jianbing, Rong, Shu, Wang, Kui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887305/ https://www.ncbi.nlm.nih.gov/pubmed/33664991 http://dx.doi.org/10.1016/j.omtn.2020.11.015

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