Alzheimer’s Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia

Microglia are key in the homeostatic well-being of the brain and microglial dysfunction has been implicated in neurodegenerative disorders such as Alzheimer’s disease (AD). Due to the many limitations to study microglia in situ or isolated for large scale drug discovery applications, there is a high...

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Detalles Bibliográficos
Autores principales: Reich, Marvin, Paris, Iñaki, Ebeling, Martin, Dahm, Nadine, Schweitzer, Christophe, Reinhardt, Dieter, Schmucki, Roland, Prasad, Megana, Köchl, Fabian, Leist, Marcel, Cowley, Sally A., Zhang, Jitao David, Patsch, Christoph, Gutbier, Simon, Britschgi, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887311/
https://www.ncbi.nlm.nih.gov/pubmed/33613545
http://dx.doi.org/10.3389/fimmu.2020.617860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887311/
https://www.ncbi.nlm.nih.gov/pubmed/33613545
http://dx.doi.org/10.3389/fimmu.2020.617860

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