Cargando…

Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer

INTRODUCTION: Dysregulation of NLRP3 inflammasome complex formation can promote chronic inflammation by increased release of IL-1β. However, the effect of NLRP3 complex formation on tumor progression remains controversial. Therefore, we sought to determine the effect of NLRP3 modulation on the growt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tezcan, Gulcin, Garanina, Ekaterina E., Alsaadi, Mohammad, Gilazieva, Zarema E., Martinova, Ekaterina V., Markelova, Maria I., Arkhipova, Svetlana S., Hamza, Shaimaa, McIntyre, Alan, Rizvanov, Albert A., Khaiboullina, Svetlana F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887322/ https://www.ncbi.nlm.nih.gov/pubmed/33613529 http://dx.doi.org/10.3389/fimmu.2020.607881

Ejemplares similares

MicroRNA Post-transcriptional Regulation of the NLRP3 Inflammasome in Immunopathologies
por: Tezcan, Gulcin, et al.
Publicado: (2019)

Doxycycline Attenuates Cancer Cell Growth by Suppressing NLRP3-Mediated Inflammation
por: Alsaadi, Mohammad, et al.
Publicado: (2021)

Blocking the Hormone Receptors Modulates NLRP3 in LPS-Primed Breast Cancer Cells
por: Hamza, Shaimaa, et al.
Publicado: (2023)

Azithromycin and Ceftriaxone Differentially Activate NLRP3 in LPS Primed Cancer Cells
por: Tezcan, Gulcin, et al.
Publicado: (2022)

Rab GTPase Mediating Regulation of NALP3 in Colorectal Cancer
por: Tezcan, Gülçin, et al.
Publicado: (2020)

Inflammasomes as Targets for Adjuvants
por: Ivanov, Konstantin, et al.
Publicado: (2020)

Genetically Engineered Artificial Microvesicles Carrying Nerve Growth Factor Restrains the Progression of Autoimmune Encephalomyelitis in an Experimental Mouse Model
por: Alatrash, Reem, et al.
Publicado: (2023)

Serum Cytokine Alterations Associated with Age of Patients with Nephropathia Epidemica
por: Shakirova, Venera, et al.
Publicado: (2022)

Immunogenic SARS-CoV-2 S and N Protein Peptide and Cytokine Combinations as Biomarkers for Early Prediction of Fatal COVID-19
por: Martynova, Ekaterina, et al.
Publicado: (2022)

Long Term Immune Response Produced by the SputnikV Vaccine
por: Martynova, Ekaterina, et al.
Publicado: (2021)

Neutralizing Antibodies in COVID-19 Serum from Tatarstan, Russia
por: Hamza, Shaimaa, et al.
Publicado: (2023)

Comparative Analysis of Natural and Cytochalasin B-Induced Membrane Vesicles from Tumor Cells and Mesenchymal Stem Cells
por: Gilazieva, Zarema, et al.
Publicado: (2022)

Inflammasome Contribution to the Activation of Th1, Th2, and Th17 Immune Responses
por: Martynova, Ekaterina, et al.
Publicado: (2022)

Antibody and T Cell Immune Responses to SARS-CoV-2 Peptides in COVID-19 Convalescent Patients
por: Garanina, Ekaterina, et al.
Publicado: (2022)

Immunogenic Properties of MVs Containing Structural Hantaviral Proteins: An Original Study
por: Shkair, Layaly, et al.
Publicado: (2022)

Human Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro
por: Chulpanova, Daria S., et al.
Publicado: (2020)

Allogenic Adipose Derived Stem Cells Transplantation Improved Sciatic Nerve Regeneration in Rats: Autologous Nerve Graft Model
por: Masgutov, Ruslan, et al.
Publicado: (2018)

Cytochalasin B-Induced Membrane Vesicles from Human Mesenchymal Stem Cells Overexpressing IL2 Are Able to Stimulate CD8(+) T-Killers to Kill Human Triple Negative Breast Cancer Cells
por: Chulpanova, Daria S., et al.
Publicado: (2021)

Membrane Microvesicles as Potential Vaccine Candidates
por: Shkair, Layaly, et al.
Publicado: (2021)

Transcriptome Profiling Reveals Pro-Inflammatory Cytokines and Matrix Metalloproteinase Activation in Zika Virus Infected Human Umbilical Vein Endothelial Cells
por: Khaiboullina, Svetlana, et al.
Publicado: (2019)

Exacerbation of Chronic Spontaneous Urticaria Symptoms in COVID-19 Patients, Case Report
por: Klyucharova, Aliya, et al.
Publicado: (2022)

Cytokine Storm Combined with Humoral Immune Response Defect in Fatal Hemorrhagic Fever with Renal Syndrome Case, Tatarstan, Russia
por: Garanina, Ekaterina, et al.
Publicado: (2019)

The Dual Role of Mesenchymal Stromal Cells and Their Extracellular Vesicles in Carcinogenesis
por: Gilazieva, Zarema, et al.
Publicado: (2022)

Structural and Functional Aspects of Ebola Virus Proteins
por: Jain, Sahil, et al.
Publicado: (2021)

Role of Viruses in the Pathogenesis of Multiple Sclerosis
por: Tarlinton, Rachael E., et al.
Publicado: (2020)

Promising Applications of Tumor Spheroids and Organoids for Personalized Medicine
por: Gilazieva, Zarema, et al.
Publicado: (2020)

Intrinsic and Extrinsic Factors Impacting Cancer Stemness and Tumor Progression
por: Ponomarev, Alexey, et al.
Publicado: (2022)

Influence of Genetically Modified Human Umbilical Cord Blood Mononuclear Cells on the Expression of Schwann Cell Molecular Determinants in Spinal Cord Injury
por: Galieva, L. R., et al.
Publicado: (2018)

Mesenchymal Stem Cell Derived Biocompatible Membrane Vesicles Demonstrate Immunomodulatory Activity Inhibiting Activation and proliferation of Human Mononuclear Cells
por: Gomzikova, Marina O., et al.
Publicado: (2020)

Cytokine, Chemokine, and Metalloprotease Activation in the Serum of Patients with Nephropathia Epidemica from the Republic of Tatarstan and the Republic of Mordovia, Russia
por: Martynova, Ekaterina, et al.
Publicado: (2021)

Δccr5 Genotype Is Associated with Mild Form of Nephropathia Epidemica
por: Kletenkov, Konstantin, et al.
Publicado: (2019)

The Interaction between Viral and Environmental Risk Factors in the Pathogenesis of Multiple Sclerosis
por: Tarlinton, Rachael Eugenie, et al.
Publicado: (2019)

High Triglycerides Are Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica
por: Martynova, Ekaterina V., et al.
Publicado: (2016)

Seasonal Changes in Serum Metabolites in Multiple Sclerosis Relapse
por: Martynova, Ekaterina, et al.
Publicado: (2023)

Hantaviral Proteins: Structure, Functions, and Role in Hantavirus Infection
por: Muyangwa, Musalwa, et al.
Publicado: (2015)

Analysis of herpesvirus infection and genome single nucleotide polymorphism risk factors in multiple sclerosis, Volga federal district, Russia
por: Lezhnyova, Vera, et al.
Publicado: (2022)

Proteomic Analysis of Human Serum from Patients with Chronic Kidney Disease
por: Romanova, Yulia, et al.
Publicado: (2020)

Orthohantaviruses, Emerging Zoonotic Pathogens
por: Kabwe, Emmanuel, et al.
Publicado: (2020)

Elevated Levels of Proinflammatory Cytokines in Cerebrospinal Fluid of Multiple Sclerosis Patients
por: Khaibullin, Timur, et al.
Publicado: (2017)

Induction of Angiogenesis by Genetically Modified Human Umbilical Cord Blood Mononuclear Cells
por: Gatina, Dilara Z., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_d2mifhnvo8c2duavikmkq3ld5b