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A scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs

Pelvic radiograph (PXR) is essential for detecting proximal femur and pelvis injuries in trauma patients, which is also the key component for trauma survey. None of the currently available algorithms can accurately detect all kinds of trauma-related radiographic findings on PXRs. Here, we show a uni...

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Autores principales: Cheng, Chi-Tung, Wang, Yirui, Chen, Huan-Wu, Hsiao, Po-Meng, Yeh, Chun-Nan, Hsieh, Chi-Hsun, Miao, Shun, Xiao, Jing, Liao, Chien-Hung, Lu, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887334/
https://www.ncbi.nlm.nih.gov/pubmed/33594071
http://dx.doi.org/10.1038/s41467-021-21311-3
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author Cheng, Chi-Tung
Wang, Yirui
Chen, Huan-Wu
Hsiao, Po-Meng
Yeh, Chun-Nan
Hsieh, Chi-Hsun
Miao, Shun
Xiao, Jing
Liao, Chien-Hung
Lu, Le
author_facet Cheng, Chi-Tung
Wang, Yirui
Chen, Huan-Wu
Hsiao, Po-Meng
Yeh, Chun-Nan
Hsieh, Chi-Hsun
Miao, Shun
Xiao, Jing
Liao, Chien-Hung
Lu, Le
author_sort Cheng, Chi-Tung
collection PubMed
description Pelvic radiograph (PXR) is essential for detecting proximal femur and pelvis injuries in trauma patients, which is also the key component for trauma survey. None of the currently available algorithms can accurately detect all kinds of trauma-related radiographic findings on PXRs. Here, we show a universal algorithm can detect most types of trauma-related radiographic findings on PXRs. We develop a multiscale deep learning algorithm called PelviXNet trained with 5204 PXRs with weakly supervised point annotation. PelviXNet yields an area under the receiver operating characteristic curve (AUROC) of 0.973 (95% CI, 0.960–0.983) and an area under the precision-recall curve (AUPRC) of 0.963 (95% CI, 0.948–0.974) in the clinical population test set of 1888 PXRs. The accuracy, sensitivity, and specificity at the cutoff value are 0.924 (95% CI, 0.912–0.936), 0.908 (95% CI, 0.885–0.908), and 0.932 (95% CI, 0.919–0.946), respectively. PelviXNet demonstrates comparable performance with radiologists and orthopedics in detecting pelvic and hip fractures.
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spelling pubmed-78873342021-03-03 A scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs Cheng, Chi-Tung Wang, Yirui Chen, Huan-Wu Hsiao, Po-Meng Yeh, Chun-Nan Hsieh, Chi-Hsun Miao, Shun Xiao, Jing Liao, Chien-Hung Lu, Le Nat Commun Article Pelvic radiograph (PXR) is essential for detecting proximal femur and pelvis injuries in trauma patients, which is also the key component for trauma survey. None of the currently available algorithms can accurately detect all kinds of trauma-related radiographic findings on PXRs. Here, we show a universal algorithm can detect most types of trauma-related radiographic findings on PXRs. We develop a multiscale deep learning algorithm called PelviXNet trained with 5204 PXRs with weakly supervised point annotation. PelviXNet yields an area under the receiver operating characteristic curve (AUROC) of 0.973 (95% CI, 0.960–0.983) and an area under the precision-recall curve (AUPRC) of 0.963 (95% CI, 0.948–0.974) in the clinical population test set of 1888 PXRs. The accuracy, sensitivity, and specificity at the cutoff value are 0.924 (95% CI, 0.912–0.936), 0.908 (95% CI, 0.885–0.908), and 0.932 (95% CI, 0.919–0.946), respectively. PelviXNet demonstrates comparable performance with radiologists and orthopedics in detecting pelvic and hip fractures. Nature Publishing Group UK 2021-02-16 /pmc/articles/PMC7887334/ /pubmed/33594071 http://dx.doi.org/10.1038/s41467-021-21311-3 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Cheng, Chi-Tung
Wang, Yirui
Chen, Huan-Wu
Hsiao, Po-Meng
Yeh, Chun-Nan
Hsieh, Chi-Hsun
Miao, Shun
Xiao, Jing
Liao, Chien-Hung
Lu, Le
A scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs
title A scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs
title_full A scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs
title_fullStr A scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs
title_full_unstemmed A scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs
title_short A scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs
title_sort scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887334/
https://www.ncbi.nlm.nih.gov/pubmed/33594071
http://dx.doi.org/10.1038/s41467-021-21311-3
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