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'Off-the-shelf’ allogeneic antigen-specific adoptive T-cell therapy for the treatment of multiple EBV-associated malignancies

BACKGROUND: Epstein-Barr virus (EBV), an oncogenic human gammaherpesvirus, is associated with a wide range of human malignancies of epithelial and B-cell origin. Recent studies have demonstrated promising safety and clinical efficacy of allogeneic ‘off-the-shelf’ virus-specific T-cell therapies for...

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Detalles Bibliográficos
Autores principales: Sinha, Debottam, Srihari, Sriganesh, Beckett, Kirrliee, Le Texier, Laetitia, Solomon, Matthew, Panikkar, Archana, Ambalathingal, George R, Lekieffre, Lea, Crooks, Pauline, Rehan, Sweera, Neller, Michelle A., Smith, Corey, Khanna, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887372/
https://www.ncbi.nlm.nih.gov/pubmed/33589524
http://dx.doi.org/10.1136/jitc-2020-001608