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The tyrosine kinase c-Abl potentiates interferon-mediated antiviral immunity by STAT1 phosphorylation
Interferon (IFN)-induced activation of the signal transducer and activator of transcription (STAT) family is an important event in antiviral immunity. Here, we show that the nonreceptor kinases c-Abl and Arg directly interact with STAT1 and potentiate the phosphorylation of STAT1 on Y701. c-Abl/Arg...
Autores principales: | Liu, Hainan, Cui, Yan, Bai, Yu, Fang, Yi, Gao, Ting, Wang, Guangfei, Zhu, Lin, Dong, Qincai, Zhang, Shuwei, Yao, Yi, Song, Caiwei, Niu, Xiayang, Jin, Yanwen, Li, Ping, Cao, Cheng, Liu, Xuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887405/ https://www.ncbi.nlm.nih.gov/pubmed/33644712 http://dx.doi.org/10.1016/j.isci.2021.102078 |
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