Characterization of a bicistronic knock-in reporter mouse model for investigating the role of CABLES2 in vivo

Two members of the CDK5 and ABL enzyme substrate (CABLES) family, CABLES1 and CABLES2, share a highly homologous C-terminus. They interact and associate with cyclin-dependent kinase 3 (CDK3), CDK5, and c-ABL. CABLES1 mediates tumor suppression, regulates cell proliferation, and prevents protein degr...

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Detalles Bibliográficos
Autores principales: Hasan, Ammar Shaker Hamed, Dinh, Tra Thi Huong, Le, Hoai Thu, Mizuno-Iijima, Saori, Daitoku, Yoko, Ishida, Miyuki, Tanimoto, Yoko, Kato, Kanako, Yoshiki, Atsushi, Murata, Kazuya, Mizuno, Seiya, Sugiyama, Fumihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2020
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887623/
https://www.ncbi.nlm.nih.gov/pubmed/32779618
http://dx.doi.org/10.1538/expanim.20-0063

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