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Development of a Web-Based Toolbox to Support Quantitative In-Vitro-to-In-Vivo Extrapolations (QIVIVE) within Nonanimal Testing Strategies

[Image: see text] The goal of the present study was to develop an online web-based toolbox that contains generic physiologically based kinetic (PBK) models for rats and humans, including underlying calculation tools to predict plasma protein binding and tissue:plasma distribution, to be used for qua...

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Detalles Bibliográficos
Autores principales:	Punt, Ans, Pinckaers, Nicole, Peijnenburg, Ad, Louisse, Jochem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887804/ https://www.ncbi.nlm.nih.gov/pubmed/33382582 http://dx.doi.org/10.1021/acs.chemrestox.0c00307

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