Iron loading is a prominent feature of activated microglia in Alzheimer’s disease patients

Brain iron accumulation has been found to accelerate disease progression in amyloid-β(Aβ) positive Alzheimer patients, though the mechanism is still unknown. Microglia have been identified as key players in the disease pathogenesis, and are highly reactive cells responding to aberrations such as inc...

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Detalles Bibliográficos
Autores principales: Kenkhuis, Boyd, Somarakis, Antonios, de Haan, Lorraine, Dzyubachyk, Oleh, IJsselsteijn, Marieke E., de Miranda, Noel F. C. C., Lelieveldt, Boudewijn P. F., Dijkstra, Jouke, van Roon-Mom, Willeke M. C., Höllt, Thomas, van der Weerd, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887813/
https://www.ncbi.nlm.nih.gov/pubmed/33597025
http://dx.doi.org/10.1186/s40478-021-01126-5

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