Immune checkpoint inhibitors

Three papers by James Allison and Tasuku Honjo published in JEM between 1995 and 2000 crystallized seminal insights into the role of CTLA-4 and PD-1 in immunosuppression (Krummel and Allison. 1995. J. Exp. Med. https://doi.org/10.1084/jem.182.2.459; van Elsas et al. 1999. J. Exp. Med. https://doi.or...

Descripción completa

Detalles Bibliográficos
Autores principales: Kroemer, Guido, Zitvogel, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Insights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888351/
https://www.ncbi.nlm.nih.gov/pubmed/33600556
http://dx.doi.org/10.1084/jem.20201979
_version_ 1783652144734273536
author Kroemer, Guido
Zitvogel, Laurence
author_facet Kroemer, Guido
Zitvogel, Laurence
author_sort Kroemer, Guido
collection PubMed
description Three papers by James Allison and Tasuku Honjo published in JEM between 1995 and 2000 crystallized seminal insights into the role of CTLA-4 and PD-1 in immunosuppression (Krummel and Allison. 1995. J. Exp. Med. https://doi.org/10.1084/jem.182.2.459; van Elsas et al. 1999. J. Exp. Med. https://doi.org/10.1084/jem.190.3.355; Freeman et al. 2000. J. Exp. Med. https://doi.org/10.1084/jem.192.7.1027). These papers laid the basis for modern cancer immunotherapy and led to a shared 2018 Nobel Prize.
format Online
Article
Text
id pubmed-7888351
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-78883512021-09-01 Immune checkpoint inhibitors Kroemer, Guido Zitvogel, Laurence J Exp Med Insights Three papers by James Allison and Tasuku Honjo published in JEM between 1995 and 2000 crystallized seminal insights into the role of CTLA-4 and PD-1 in immunosuppression (Krummel and Allison. 1995. J. Exp. Med. https://doi.org/10.1084/jem.182.2.459; van Elsas et al. 1999. J. Exp. Med. https://doi.org/10.1084/jem.190.3.355; Freeman et al. 2000. J. Exp. Med. https://doi.org/10.1084/jem.192.7.1027). These papers laid the basis for modern cancer immunotherapy and led to a shared 2018 Nobel Prize. Rockefeller University Press 2021-02-16 /pmc/articles/PMC7888351/ /pubmed/33600556 http://dx.doi.org/10.1084/jem.20201979 Text en © 2021 Kroemer and Zitvogel http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Insights
Kroemer, Guido
Zitvogel, Laurence
Immune checkpoint inhibitors
title Immune checkpoint inhibitors
title_full Immune checkpoint inhibitors
title_fullStr Immune checkpoint inhibitors
title_full_unstemmed Immune checkpoint inhibitors
title_short Immune checkpoint inhibitors
title_sort immune checkpoint inhibitors
topic Insights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888351/
https://www.ncbi.nlm.nih.gov/pubmed/33600556
http://dx.doi.org/10.1084/jem.20201979
work_keys_str_mv AT kroemerguido immunecheckpointinhibitors
AT zitvogellaurence immunecheckpointinhibitors

Ejemplares similares