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Risk factors associated with serious bacterial infections among newborns with high body temperature
INTRODUCTION: Recognizing the importance of serious bacterial infections (SBIs), study aimed to identify factors associated with high body temperature in newborns. METHODS: A convenience sample of 54 newborns admitted to our hospital in Iran (March-July 2015) with rectal temperature > 38°C (100.4...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pacini Editore Srl
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888388/ https://www.ncbi.nlm.nih.gov/pubmed/33628961 http://dx.doi.org/10.15167/2421-4248/jpmh2020.61.4.1461 |
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author | NASEH, ALI TASLIMI-TALEGHANI, NAEEME |
author_facet | NASEH, ALI TASLIMI-TALEGHANI, NAEEME |
author_sort | NASEH, ALI |
collection | PubMed |
description | INTRODUCTION: Recognizing the importance of serious bacterial infections (SBIs), study aimed to identify factors associated with high body temperature in newborns. METHODS: A convenience sample of 54 newborns admitted to our hospital in Iran (March-July 2015) with rectal temperature > 38°C (100.4°F) were examined for clinical signs, blood cultures, complete blood counts, platelets, Erythrocyte Sedimentation Rate (ESR), C-reactive protein (CRP), renal function, chest/abdominal x-rays, spinal tap, and history of maternal infections. RESULTS: Newborns had either fever due to infections, or hyperthermia due to dehydration and/or extreme warm environment. Bacterial infections (37%) included: sepsis (15%) (coagulase-positive or coagulase-negative Staphylococci, Enterobacter, Klebsiella, Escherichia coli), meningitis (13%), and 3.5% UTI, 3.5% pneumonia, 2% cellulitis, and 2% omphalitis. Degrees of dehydration experienced by 55.6% included 37% of cases associated with hyperthermia caused by warm clothing/environment, while in 18.6% dehydration was secondary to fever. Viral infections (11%) included upper respiratory infections, gastroenteritis, while in remaining 13% cause of high body temperature was unknown. The group with SBIs had higher chance of having history of PROM (premature rupture of membrane) (p = 0.023), positive CRP (p = 0.041), and abnormal platelets count (p = 0.021) comparing all others. CONCLUSIONS: High body temperature in newborns needs careful evaluation to identify fever due to SBIs. In sepsis cases, antibiotics should cover prevalent bacteria including Staphylococci and Enterobacter. Dehydration was prevalent among newborns with high body temperature due to hyperthermia or secondary to infections. To avoid hyperthermia, parents should know how to clothe their newborns appropriate for environmental temperature. Newborns’ SBIs associated with positive CRP, abnormal platelet count, and maternal PROM. |
format | Online Article Text |
id | pubmed-7888388 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Pacini Editore Srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-78883882021-02-23 Risk factors associated with serious bacterial infections among newborns with high body temperature NASEH, ALI TASLIMI-TALEGHANI, NAEEME J Prev Med Hyg Original Article INTRODUCTION: Recognizing the importance of serious bacterial infections (SBIs), study aimed to identify factors associated with high body temperature in newborns. METHODS: A convenience sample of 54 newborns admitted to our hospital in Iran (March-July 2015) with rectal temperature > 38°C (100.4°F) were examined for clinical signs, blood cultures, complete blood counts, platelets, Erythrocyte Sedimentation Rate (ESR), C-reactive protein (CRP), renal function, chest/abdominal x-rays, spinal tap, and history of maternal infections. RESULTS: Newborns had either fever due to infections, or hyperthermia due to dehydration and/or extreme warm environment. Bacterial infections (37%) included: sepsis (15%) (coagulase-positive or coagulase-negative Staphylococci, Enterobacter, Klebsiella, Escherichia coli), meningitis (13%), and 3.5% UTI, 3.5% pneumonia, 2% cellulitis, and 2% omphalitis. Degrees of dehydration experienced by 55.6% included 37% of cases associated with hyperthermia caused by warm clothing/environment, while in 18.6% dehydration was secondary to fever. Viral infections (11%) included upper respiratory infections, gastroenteritis, while in remaining 13% cause of high body temperature was unknown. The group with SBIs had higher chance of having history of PROM (premature rupture of membrane) (p = 0.023), positive CRP (p = 0.041), and abnormal platelets count (p = 0.021) comparing all others. CONCLUSIONS: High body temperature in newborns needs careful evaluation to identify fever due to SBIs. In sepsis cases, antibiotics should cover prevalent bacteria including Staphylococci and Enterobacter. Dehydration was prevalent among newborns with high body temperature due to hyperthermia or secondary to infections. To avoid hyperthermia, parents should know how to clothe their newborns appropriate for environmental temperature. Newborns’ SBIs associated with positive CRP, abnormal platelet count, and maternal PROM. Pacini Editore Srl 2021-01-14 /pmc/articles/PMC7888388/ /pubmed/33628961 http://dx.doi.org/10.15167/2421-4248/jpmh2020.61.4.1461 Text en ©2020 Pacini Editore SRL, Pisa, Italy https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en This is an open access article distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license. The article can be used by giving appropriate credit and mentioning the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en |
spellingShingle | Original Article NASEH, ALI TASLIMI-TALEGHANI, NAEEME Risk factors associated with serious bacterial infections among newborns with high body temperature |
title | Risk factors associated with serious bacterial infections among newborns with high body temperature |
title_full | Risk factors associated with serious bacterial infections among newborns with high body temperature |
title_fullStr | Risk factors associated with serious bacterial infections among newborns with high body temperature |
title_full_unstemmed | Risk factors associated with serious bacterial infections among newborns with high body temperature |
title_short | Risk factors associated with serious bacterial infections among newborns with high body temperature |
title_sort | risk factors associated with serious bacterial infections among newborns with high body temperature |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888388/ https://www.ncbi.nlm.nih.gov/pubmed/33628961 http://dx.doi.org/10.15167/2421-4248/jpmh2020.61.4.1461 |
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