IRGM promotes melanoma cell survival through autophagy and is a promising prognostic biomarker for clinical application

Previously, we showed that mouse immunity-related guanosine triphosphatase (GTPase) family M protein 1 (Irgm1) promotes malignant melanoma progression by inducing cellular autophagy flux and metastasis. Human IRGM, a truncated protein functionally distinct from its mouse counterpart, has several spl...

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Detalles Bibliográficos
Autores principales: Tian, Linlu, Meng, Hongxue, Dong, Xiao, Li, Xinlei, Shi, Zilin, Li, Hulun, Zhang, Lie, Yang, Yue, Liu, Ruijie, Pei, Chunying, Li, Bo, Xu, Hongwei, Li, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889451/
https://www.ncbi.nlm.nih.gov/pubmed/33665357
http://dx.doi.org/10.1016/j.omto.2020.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889451/
https://www.ncbi.nlm.nih.gov/pubmed/33665357
http://dx.doi.org/10.1016/j.omto.2020.12.005

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