Imaging assay to probe the role of telomere length shortening on telomere-gene interactions in single cells

Telomeres are repetitive non-coding nucleotide sequences (TTAGGGn) capping the ends of chromosomes. Progressive telomere shortening with increasing age has been associated with shifts in gene expression through models such as the telomere position effect (TPE), which suggests reduced interference of...

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Detalles Bibliográficos
Autores principales: Zhang, Ning, Li, Yanhui, Lai, Tsung-Po, Shay, Jerry W., Danuser, Gaudenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889534/
https://www.ncbi.nlm.nih.gov/pubmed/33555479
http://dx.doi.org/10.1007/s00412-020-00747-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889534/
https://www.ncbi.nlm.nih.gov/pubmed/33555479
http://dx.doi.org/10.1007/s00412-020-00747-4

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