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A deformation energy model reveals sequence-dependent property of nucleosome positioning

We present a deformation energy model for predicting nucleosome positioning, in which a position-dependent structural parameter set derived from crystal structures of nucleosomes was used to calculate the DNA deformation energy. The model is successful in predicting nucleosome occupancy genome-wide...

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Detalles Bibliográficos
Autores principales: Liu, Guoqing, Zhao, Hongyu, Meng, Hu, Xing, Yongqiang, Cai, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889546/
https://www.ncbi.nlm.nih.gov/pubmed/33452566
http://dx.doi.org/10.1007/s00412-020-00750-9

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