A genetically stable Zika virus vaccine candidate protects mice against virus infection and vertical transmission

Although live attenuated vaccines (LAVs) have been effective in the control of flavivirus infections, to date they have been excluded from Zika virus (ZIKV) vaccine trials due to safety concerns. We have previously reported two ZIKV mutants, each of which has a single substitution in either envelope...

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Detalles Bibliográficos
Autores principales: Adam, Awadalkareem, Fontes-Garfias, Camila R., Sarathy, Vanessa V., Liu, Yang, Luo, Huanle, Davis, Emily, Li, Wenqian, Muruato, Antonio E., Wang, Binbin, Ahatov, Renat, Mahmoud, Yoseph, Shan, Chao, Osman, Samantha R., Widen, Steven G., Barrett, Alan D. T., Shi, Pei-Yong, Wang, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889622/
https://www.ncbi.nlm.nih.gov/pubmed/33597526
http://dx.doi.org/10.1038/s41541-021-00288-6

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