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Machine learning classifies predictive kinematic features in a mouse model of neurodegeneration

Motor deficits are observed in Alzheimer’s disease (AD) prior to the appearance of cognitive symptoms. To investigate the role of amyloid proteins in gait disturbances, we characterized locomotion in APP-overexpressing transgenic J20 mice. We used three-dimensional motion capture to characterize qua...

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Detalles Bibliográficos
Autores principales:	Huang, Ruyi, Nikooyan, Ali A., Xu, Bo, Joseph, M. Selvan, Damavandi, Hamidreza Ghasemi, von Trotha, Nathan, Li, Lilian, Bhattarai, Ashok, Zadeh, Deeba, Seo, Yeji, Liu, Xingquan, Truong, Patrick A., Koo, Edward H., Leiter, J. C., Lu, Daniel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889656/ https://www.ncbi.nlm.nih.gov/pubmed/33597593 http://dx.doi.org/10.1038/s41598-021-82694-3

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