Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections

BACKGROUND: Thresholds for SARS-CoV-2 antibody assays have typically been determined using samples from symptomatic, often hospitalised, patients. In this setting the sensitivity and specificity of the best performing assays can both exceed 98%. However, antibody assay performance following mild inf...

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Detalles Bibliográficos
Autores principales: Eyre, David W., Lumley, Sheila F., O’Donnell, Denise, Stoesser, Nicole E., Matthews, Philippa C., Howarth, Alison, Hatch, Stephanie B., Marsden, Brian D., Cox, Stuart, James, Tim, Cornall, Richard J., Stuart, David I., Screaton, Gavin, Ebner, Daniel, Crook, Derrick W., Conlon, Christopher P., Jeffery, Katie, Walker, Timothy M., Peto, Timothy E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889711/
https://www.ncbi.nlm.nih.gov/pubmed/33602152
http://dx.doi.org/10.1186/s12879-021-05878-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889711/
https://www.ncbi.nlm.nih.gov/pubmed/33602152
http://dx.doi.org/10.1186/s12879-021-05878-2

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