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Stability and folding pathways of tetra-nucleosome from six-dimensional free energy surface
The three-dimensional organization of chromatin is expected to play critical roles in regulating genome functions. High-resolution characterization of its structure and dynamics could improve our understanding of gene regulation mechanisms but has remained challenging. Using a near-atomistic model t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889939/ https://www.ncbi.nlm.nih.gov/pubmed/33597548 http://dx.doi.org/10.1038/s41467-021-21377-z |