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Endothelial YAP/TAZ Signaling in Angiogenesis and Tumor Vasculature

Solid tumors are dependent on vascularization for their growth. The hypoxic, stiff, and pro-angiogenic tumor microenvironment induces angiogenesis, giving rise to an immature, proliferative, and permeable vasculature. The tumor vessels promote tumor metastasis and complicate delivery of anti-cancer...

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Detalles Bibliográficos
Autores principales: Hooglugt, Aukie, van der Stoel, Miesje M., Boon, Reinier A., Huveneers, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890025/
https://www.ncbi.nlm.nih.gov/pubmed/33614496
http://dx.doi.org/10.3389/fonc.2020.612802