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Endothelial YAP/TAZ Signaling in Angiogenesis and Tumor Vasculature
Solid tumors are dependent on vascularization for their growth. The hypoxic, stiff, and pro-angiogenic tumor microenvironment induces angiogenesis, giving rise to an immature, proliferative, and permeable vasculature. The tumor vessels promote tumor metastasis and complicate delivery of anti-cancer...
Autores principales: | Hooglugt, Aukie, van der Stoel, Miesje M., Boon, Reinier A., Huveneers, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890025/ https://www.ncbi.nlm.nih.gov/pubmed/33614496 http://dx.doi.org/10.3389/fonc.2020.612802 |
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