Cargando…

Safe and effective delivery of supplemental iron to healthy older adults: The double-blind, randomized, placebo-controlled trial protocol of the Safe Iron Study

The forms of iron currently available to correct iron deficiency have adverse effects, including infectious diarrhea, increased susceptibility to malaria, inflammation and detrimental changes to the gut microbiome. These adverse effects limit their use such that the growing burden of iron deficiency...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lewis, Erin D., Wu, Dayong, Mason, Joel B., Chishti, Athar H., Leong, John M., Barger, Kathryn, Meydani, Simin N., Combs, Gerald F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000 Research Limited 2021
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890045/ https://www.ncbi.nlm.nih.gov/pubmed/33655197 http://dx.doi.org/10.12688/gatesopenres.13039.2

Ejemplares similares

Safe and effective delivery of supplemental iron to healthy adults: a two-phase, randomized, double-blind trial – the safe iron study
por: Lewis, Erin D., et al.
Publicado: (2023)

A novel nano-iron supplement to safely combat iron deficiency and anaemia in young children: The IHAT-GUT double-blind, randomised, placebo-controlled trial protocol
por: Pereira, Dora I.A., et al.
Publicado: (2018)

A double blind randomised controlled trial comparing standard dose of iron supplementation for pregnant women with two screen-and-treat approaches using hepcidin as a biomarker for ready and safe to receive iron
por: Bah, Amat, et al.
Publicado: (2016)

Alternate day versus consecutive day oral iron supplementation in iron-depleted women: a randomized double-blind placebo-controlled study
por: von Siebenthal, Hanna K., et al.
Publicado: (2023)

Nanoparticulate iron(III) oxo-hydroxide delivers safe iron that is well absorbed and utilised in humans
por: Pereira, Dora I.A., et al.
Publicado: (2014)

Design of Safe Nanotherapeutics for the Excretion of Excess Systemic Toxic Iron
por: Abbina, Srinivas, et al.
Publicado: (2019)

Obesity during Pregnancy and Fetal Iron Status: is Hepcidin the link?
por: Dao, Maria Carlota, et al.
Publicado: (2012)

High Iron and Iron Household Protein Contents in Perineuronal Net-Ensheathed Neurons Ensure Energy Metabolism with Safe Iron Handling
por: Reinert, Anja, et al.
Publicado: (2022)

Ferric citrate is a safe and digestible source of iron in broilers and piglets
por: Männer, Klaus, et al.
Publicado: (2021)

Nutritional Modulation of Immune Function: Analysis of Evidence, Mechanisms, and Clinical Relevance
por: Wu, Dayong, et al.
Publicado: (2019)

Modification of the surface of superparamagnetic iron oxide nanoparticles to enable their safe application in humans
por: Strehl, Cindy, et al.
Publicado: (2016)

ZINC AND MULTIVITAMIN SUPPLEMENTATION HAVE CONTRASTING EFFECTS ON INFANT IRON STATUS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL TRIAL
por: Carter, R. Colin, et al.
Publicado: (2017)

Safe Use of Herbal Kelp Supplements
por: McGuffin, Michael, et al.
Publicado: (2007)

Green synthesis of safe zero valent iron nanoparticles by Myrtus communis leaf extract as an effective agent for reducing excessive iron in iron-overloaded mice, a thalassemia model
por: Eslami, Shahram, et al.
Publicado: (2018)

Effect of acute iron infusion on insulin secretion: A randomized, double-blind, placebo-controlled trial
por: Jaccard, Evrim, et al.
Publicado: (2022)

Long-Term Supplementation with Fruits and Vegetables Prolongs Lifespan and Reduces Tumor Incidence in Mice Fed a Western-Style High-Fat Diet
por: Guo, Weimin, et al.
Publicado: (2022)

Ambulatory laparoscopic cholecystectomy: Is it safe and cost effective?
por: Ali, Athar, et al.
Publicado: (2009)

Effect of vitamin D(3) supplementation on iron status: a randomized, double-blind, placebo-controlled trial among ethnic minorities living in Norway
por: Madar, Ahmed A., et al.
Publicado: (2016)

Iron status of exclusively breastfed low-birth-weight infants born to anemic mothers and effect of maternal iron supplementation for 3 versus 6 months: A randomized double-blind placebo control trial
por: Fatima, Tarannum, et al.
Publicado: (2022)

Iron metabolism and iron supplementation in cancer patients
por: Ludwig, Heinz, et al.
Publicado: (2015)

Iron Supplements for Infants at Risk for Iron Deficiency
por: MacQueen, Brianna C., et al.
Publicado: (2017)

Long-Term Supplementation With Fruits and Vegetables Prevents Western-Style High-Fat Diet-Induced Cognitive Impairment in Mice
por: Guo, Weimin, et al.
Publicado: (2022)

Micronized, Microencapsulated Ferric Iron Supplementation in the Form of >Your< Iron Syrup Improves Hemoglobin and Ferritin Levels in Iron-Deficient Children: Double-Blind, Randomized Clinical Study of Efficacy and Safety
por: Zečkanović, Aida, et al.
Publicado: (2021)

On the Origins of Some Spectroscopic Properties of “Purple Iron” (the Tetraoxoferrate(VI) Ion) and Its Pourbaix Safe-Space
por: Cheung, Philip C.W., et al.
Publicado: (2021)

Erratum to: Iron metabolism and iron supplementation in cancer patients
por: Ludwig, Heinz, et al.
Publicado: (2015)

Multiple micronutrient supplements versus iron‐folic acid supplements and maternal anemia outcomes: an iron dose analysis
por: Gomes, Filomena, et al.
Publicado: (2022)

Iron Chelator or Iron Supplement Consumption in COVID-19? The Role of Iron with Severity Infection
por: Bastin, Alireza, et al.
Publicado: (2021)

How safe is safe, and where are we in the journey toward safest of safe?
por: Dar, Lalit, et al.
Publicado: (2017)

Human health risk assessment of elevated and variable iron and manganese intake with arsenic-safe groundwater in Jashore, Bangladesh
por: Ghosh, Gopal Chandra, et al.
Publicado: (2020)

Food-specific sublingual immunotherapy is well tolerated and safe in healthy dogs: a blind, randomized, placebo-controlled study
por: Maina, E., et al.
Publicado: (2017)

Prevalence of adulteration in dietary supplements and recommendations for safe supplement practices in sport
por: Jagim, Andrew R., et al.
Publicado: (2023)

Effectiveness of Iron Supplementation in Reducing Iron Deficiency Anemia in India
por: Gupta, Aakriti, et al.
Publicado: (2017)

Rationale and design of the IRON-AF study: a double-blind, randomised, placebo-controlled study to assess the effect of intravenous ferric carboxymaltose in patients with atrial fibrillation and iron deficiency
por: Tu, Samuel J, et al.
Publicado: (2021)

Development of Safe and Effective Botanical Dietary Supplements: Miniperspective
por: van Breemen, Richard B.
Publicado: (2015)

Nattospes as Effective and Safe Functional Supplements in Management of Stroke
por: Pham, Phuong T., et al.
Publicado: (2020)

Vitamin D Supplements: Over-the-Counter Accessibility... It Is Safe?
por: Figueroa-Cruz, Alegyari, et al.
Publicado: (2021)

Effect of multiple micronutrient supplements v. iron and folic acid supplements on neonatal mortality: a reanalysis by iron dose
por: Gomes, Filomena, et al.
Publicado: (2022)

Early Probiotic Supplementation of Healthy Term Infants with Bifidobacterium longum subsp. infantis M-63 Is Safe and Leads to the Development of Bifidobacterium-Predominant Gut Microbiota: A Double-Blind, Placebo-Controlled Trial
por: Hiraku, Akari, et al.
Publicado: (2023)

Neurological development and iron supplementation in healthy late-preterm neonates: a randomized double-blind controlled trial
por: Luciano, R., et al.
Publicado: (2021)

Protocol for a randomised, multicentre, four-arm, double-blinded, placebo-controlled trial to assess the benefits and safety of iron supplementation with malaria chemoprevention to children in Malawi: IRMA trial
por: Mwangi, Martin N., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hufe3e2pga7r5hq8skgnp7cfu6