Impaired NEPHRIN localization in kidney organoids derived from nephrotic patient iPS cells

Mutations in the NPHS1 gene, which encodes NEPHRIN, cause congenital nephrotic syndrome, resulting from impaired slit diaphragm (SD) formation in glomerular podocytes. We previously reported NEPHRIN and SD abnormalities in the podocytes of kidney organoids generated from patient-derived induced plur...

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Detalles Bibliográficos
Autores principales: Ohmori, Tomoko, De, Shankhajit, Tanigawa, Shunsuke, Miike, Koichiro, Islam, Mazharul, Soga, Minami, Era, Takumi, Shiona, Shinichi, Nakanishi, Koichi, Nakazato, Hitoshi, Nishinakamura, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890052/
https://www.ncbi.nlm.nih.gov/pubmed/33597637
http://dx.doi.org/10.1038/s41598-021-83501-9

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