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MYD88 signals induce tumour-initiating cell generation through the NF-κB-HIF-1α activation cascade

Tumour-promoting inflammation is a hallmark of cancer, and chronic inflammatory disease increases the risk of cancer. In this context, MYD88, a downstream signalling molecule of Toll-like receptors that initiates inflammatory signalling cascades, has a critical role in tumour development in mice and...

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Detalles Bibliográficos
Autores principales: Tanimura, Atsuko, Nakazato, Akane, Tanaka, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890054/
https://www.ncbi.nlm.nih.gov/pubmed/33597599
http://dx.doi.org/10.1038/s41598-021-83603-4