TAK1 inhibition improves myoblast differentiation and alleviates fibrosis in a mouse model of Duchenne muscular dystrophy

BACKGROUND: Transforming growth factor‐β‐activated kinase 1 (TAK1) plays a key role in regulating fibroblast and myoblast proliferation and differentiation. However, the TAK1 changes associated with Duchenne muscular dystrophy (DMD) are poorly understood, and it remains unclear how TAK1 regulation c...

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Detalles Bibliográficos
Autores principales: Xu, Dengqiu, Li, Sijia, Wang, Lu, Jiang, Jingwei, Zhao, Lei, Huang, Xiaofei, Sun, Zeren, Li, Chunjie, Sun, Lixin, Li, Xihua, Jiang, Zhenzhou, Zhang, Luyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890152/
https://www.ncbi.nlm.nih.gov/pubmed/33236534
http://dx.doi.org/10.1002/jcsm.12650

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