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AMPK-mTOR-ULK1-mediated autophagy protects carbon tetrachloride-induced acute hepatic failure by inhibiting p21 in rats

Autophagy is a lysosomal-dependent degradation pathway in eukaryotic cells. Recent studies have reported that autophagy can facilitate the activation of hepatic stellate cells (HSCs) and fibrogenesis of the liver during long-term carbon tetrachloride (CCl(4)) exposure. However, little is known about...

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Detalles Bibliográficos
Autores principales:	Wang, Qiwen, Liu, Weixia, Liu, Gaopeng, Li, Pan, Guo, Xueqiang, Zhang, Chunyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Society of Toxicologic Pathology 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890163/ https://www.ncbi.nlm.nih.gov/pubmed/33627946 http://dx.doi.org/10.1293/tox.2020-0022

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