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Effects of Excess Brain-Derived Human α-Synuclein on Synaptic Vesicle Trafficking

α-Synuclein is a presynaptic protein that regulates synaptic vesicle trafficking under physiological conditions. However, in several neurodegenerative diseases, including Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy, α-synuclein accumulates throughout the neuron, inclu...

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Detalles Bibliográficos
Autores principales:	Román-Vendrell, Cristina, Medeiros, Audrey T., Sanderson, John B., Jiang, Haiyang, Bartels, Tim, Morgan, Jennifer R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890186/ https://www.ncbi.nlm.nih.gov/pubmed/33613189 http://dx.doi.org/10.3389/fnins.2021.639414

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