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Essential roles of insulin and IGF-1 receptors during embryonic lineage development

The insulin and insulin-like growth factor-1 (IGF-1) receptors are important for the growth and development of embryonic tissues. To directly define their roles in the maintenance of pluripotency and differentiation of stem cells, we knocked out both receptors in induced pluripotent stem cells (iPSC...

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Detalles Bibliográficos
Autores principales: Okawa, Erin R., Gupta, Manoj K., Kahraman, Sevim, Goli, Praneeth, Sakaguchi, Masaji, Hu, Jiang, Duan, Kaiti, Slipp, Brittany, Lennerz, Jochen K., Kulkarni, Rohit N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890209/
https://www.ncbi.nlm.nih.gov/pubmed/33453419
http://dx.doi.org/10.1016/j.molmet.2021.101164