Cargando…

Essential roles of insulin and IGF-1 receptors during embryonic lineage development

The insulin and insulin-like growth factor-1 (IGF-1) receptors are important for the growth and development of embryonic tissues. To directly define their roles in the maintenance of pluripotency and differentiation of stem cells, we knocked out both receptors in induced pluripotent stem cells (iPSC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Okawa, Erin R., Gupta, Manoj K., Kahraman, Sevim, Goli, Praneeth, Sakaguchi, Masaji, Hu, Jiang, Duan, Kaiti, Slipp, Brittany, Lennerz, Jochen K., Kulkarni, Rohit N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890209/ https://www.ncbi.nlm.nih.gov/pubmed/33453419 http://dx.doi.org/10.1016/j.molmet.2021.101164

Ejemplares similares

Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation
por: Gupta, Manoj K., et al.
Publicado: (2018)

Leptin Receptor Signaling Regulates Protein Synthesis Pathways and Neuronal Differentiation in Pluripotent Stem Cells
por: Gupta, Manoj K., et al.
Publicado: (2020)

m(6)A mRNA Methylation Regulates Human β-Cell Biology in Physiological States and in Type 2 Diabetes
por: De Jesus, Dario F, et al.
Publicado: (2019)

Single-nucleus RNA-Seq reveals singular gene signatures of human ductal cells during adaptation to insulin resistance
por: Dirice, Ercument, et al.
Publicado: (2022)

Using single-nucleus RNA-sequencing to interrogate transcriptomic profiles of archived human pancreatic islets
por: Basile, Giorgio, et al.
Publicado: (2021)

IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche
por: Wamaitha, Sissy E., et al.
Publicado: (2020)

Harnessing reaction-based probes to preferentially target pancreatic β-cells and β-like cells
por: Kahraman, Sevim, et al.
Publicado: (2021)

Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression
por: Cai, Weikang, et al.
Publicado: (2017)

ERG is required for the differentiation of embryonic stem cells along the endothelial lineage
por: Nikolova-Krstevski, Vesna, et al.
Publicado: (2009)

STRA6 is essential for induction of vascular smooth muscle lineages in human embryonic cardiac outflow tract development
por: Zhou, Chikai, et al.
Publicado: (2023)

Cell surface fluctuations regulate early embryonic lineage sorting
por: Yanagida, Ayaka, et al.
Publicado: (2022)

Cell surface fluctuations regulate early embryonic lineage sorting
por: Yanagida, Ayaka, et al.
Publicado: (2022)

Dissecting embryonic and extra-embryonic lineage crosstalk with stem cell co-culture
por: Wei, Yulei, et al.
Publicado: (2023)

Lineage tracing of Foxd1‐expressing embryonic progenitors to assess the role of divergent embryonic lineages on adult dermal fibroblast function
por: Walker, John T., et al.
Publicado: (2021)

Sequential activation of uterine epithelial IGF1R by stromal IGF1 and embryonic IGF2 directs normal uterine preparation for embryo implantation
por: Zhou, Chan, et al.
Publicado: (2021)

Double-punching PMBL
por: Lennerz, Jochen K.
Publicado: (2014)

Role of IGF1R in Breast Cancer Subtypes, Stemness, and Lineage Differentiation
por: Farabaugh, Susan M., et al.
Publicado: (2015)

Zygotic vinculin is not essential for embryonic development in zebrafish
por: Han, Mitchell K. L., et al.
Publicado: (2017)

Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses
por: Kahraman, Sevim, et al.
Publicado: (2023)

Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia
por: St-Louis, Johanna L., et al.
Publicado: (2023)

Early lineage segregation of multipotent embryonic mammary gland progenitors
por: Wuidart, Aline, et al.
Publicado: (2018)

The Role of Polycomb Proteins in Cell Lineage Commitment and Embryonic Development
por: Loh, Chet H., et al.
Publicado: (2022)

Fam40b is required for lineage commitment of murine embryonic stem cells
por: Wagh, V, et al.
Publicado: (2014)

Implementing Keytruda/Pembrolizumab Testing in Clinical Practice
por: Ratner, Dmitry, et al.
Publicado: (2018)

Sustainable development goals applied to digital pathology and artificial intelligence applications in low- to middle-income countries
por: Piya, Sumi, et al.
Publicado: (2023)

Human embryonic stem cells contribute to embryonic and extraembryonic lineages in mouse embryos upon inhibition of apoptosis
por: Wang, Xuepeng, et al.
Publicado: (2018)

Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming
por: Senft, Anna D., et al.
Publicado: (2018)

Soluble Factors Secreted by T Cells Promote β-Cell Proliferation
por: Dirice, Ercument, et al.
Publicado: (2014)

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function
por: Boucher, Jeremie, et al.
Publicado: (2016)

Lineage-specific proteins essential for endocytosis in trypanosomes
por: Manna, Paul T., et al.
Publicado: (2017)

MICAL2 is essential for myogenic lineage commitment
por: Giarratana, Nefele, et al.
Publicado: (2020)

STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
por: Jin, Lin, et al.
Publicado: (2020)

Transcriptional analysis of early lineage commitment in human embryonic stem cells
por: Laslett, Andrew L, et al.
Publicado: (2007)

Notch Promotes Neural Lineage Entry by Pluripotent Embryonic Stem Cells
por: Lowell, Sally, et al.
Publicado: (2006)

Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5
por: Ng, Ray Kit, et al.
Publicado: (2008)

Plectus - a stepping stone in embryonic cell lineage evolution of nematodes
por: Schulze, Jens, et al.
Publicado: (2012)

Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators
por: Wei, Shu, et al.
Publicado: (2016)

Graphene Oxide promotes embryonic stem cell differentiation to haematopoietic lineage
por: Garcia-Alegria, Eva, et al.
Publicado: (2016)

Polycomb enables primitive endoderm lineage priming in embryonic stem cells
por: Illingworth, Robert S, et al.
Publicado: (2016)

Ronin governs the metabolic capacity of the embryonic lineage for post‐implantation development
por: Salewskij, Kirill, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j6bfb3711eoj5b6a095rf944nf