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Prognostic Importance of Multiple Nutrition Screening Indexes for 1-Year Mortality in Hospitalized Acute Decompensated Heart Failure Patients

Background: The purpose of the study was to evaluate the impact of nutritional status on 1-year mortality in hospitalized patients with acute decompensated heart failure (ADHF). Methods and Results: We enrolled 457 hospitalized ADHF patients. Previously established objective nutritional indexes (con...

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Autores principales: Takikawa, Tomonobu, Sumi, Takuya, Takahara, Kunihiko, Kawamura, Yoshihiro, Ohguchi, Shioh, Oguri, Mitsutoshi, Ishii, Hideki, Murohara, Toyoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Circulation Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890280/
https://www.ncbi.nlm.nih.gov/pubmed/33693118
http://dx.doi.org/10.1253/circrep.CR-18-0018
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author Takikawa, Tomonobu
Sumi, Takuya
Takahara, Kunihiko
Kawamura, Yoshihiro
Ohguchi, Shioh
Oguri, Mitsutoshi
Ishii, Hideki
Murohara, Toyoaki
author_facet Takikawa, Tomonobu
Sumi, Takuya
Takahara, Kunihiko
Kawamura, Yoshihiro
Ohguchi, Shioh
Oguri, Mitsutoshi
Ishii, Hideki
Murohara, Toyoaki
author_sort Takikawa, Tomonobu
collection PubMed
description Background: The purpose of the study was to evaluate the impact of nutritional status on 1-year mortality in hospitalized patients with acute decompensated heart failure (ADHF). Methods and Results: We enrolled 457 hospitalized ADHF patients. Previously established objective nutritional indexes (controlling nutritional status [CONUT], prognostic nutritional index [PNI], geriatric nutritional risk index [GNRI], and subjective global assessment [SGA]) were evaluated at hospital admission. Malnutrition was defined as CONUT score ≥5, PNI score <38, GNRI score <92, and SGA scores B and C. The frequencies of malnutrition based on CONUT, PNI, GNRI, and SGA were 31.5%, 21.4%, 44.9%, and 27.8%, respectively. All indexes were related to the occurrence of 1-year mortality on univariate Cox regression analysis (P<0.05). We constructed a reference model using age, body mass index, systolic blood pressure, sodium concentration, and renal function on multivariable Cox regression analysis. Adding SGA to the reference model significantly improved both net reclassification improvement (NRI) and integrated discrimination improvement (0.344, P=0.002; 0.012, P=0.049; respectively). Other indexes (CONUT, PNI, and GNRI scores) significantly improved NRI (0.254, P=0.019; 0.273, P=0.013; 0.306, P=0.006; respectively). Conclusions: Nutritional screening assessed at hospital admission was appropriate for the prediction of 1-year mortality in hospitalized patients with ADHF.
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spelling pubmed-78902802021-03-09 Prognostic Importance of Multiple Nutrition Screening Indexes for 1-Year Mortality in Hospitalized Acute Decompensated Heart Failure Patients Takikawa, Tomonobu Sumi, Takuya Takahara, Kunihiko Kawamura, Yoshihiro Ohguchi, Shioh Oguri, Mitsutoshi Ishii, Hideki Murohara, Toyoaki Circ Rep Original article Background: The purpose of the study was to evaluate the impact of nutritional status on 1-year mortality in hospitalized patients with acute decompensated heart failure (ADHF). Methods and Results: We enrolled 457 hospitalized ADHF patients. Previously established objective nutritional indexes (controlling nutritional status [CONUT], prognostic nutritional index [PNI], geriatric nutritional risk index [GNRI], and subjective global assessment [SGA]) were evaluated at hospital admission. Malnutrition was defined as CONUT score ≥5, PNI score <38, GNRI score <92, and SGA scores B and C. The frequencies of malnutrition based on CONUT, PNI, GNRI, and SGA were 31.5%, 21.4%, 44.9%, and 27.8%, respectively. All indexes were related to the occurrence of 1-year mortality on univariate Cox regression analysis (P<0.05). We constructed a reference model using age, body mass index, systolic blood pressure, sodium concentration, and renal function on multivariable Cox regression analysis. Adding SGA to the reference model significantly improved both net reclassification improvement (NRI) and integrated discrimination improvement (0.344, P=0.002; 0.012, P=0.049; respectively). Other indexes (CONUT, PNI, and GNRI scores) significantly improved NRI (0.254, P=0.019; 0.273, P=0.013; 0.306, P=0.006; respectively). Conclusions: Nutritional screening assessed at hospital admission was appropriate for the prediction of 1-year mortality in hospitalized patients with ADHF. The Japanese Circulation Society 2019-01-11 /pmc/articles/PMC7890280/ /pubmed/33693118 http://dx.doi.org/10.1253/circrep.CR-18-0018 Text en Copyright © 2019, THE JAPANESE CIRCULATION SOCIETY This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Original article
Takikawa, Tomonobu
Sumi, Takuya
Takahara, Kunihiko
Kawamura, Yoshihiro
Ohguchi, Shioh
Oguri, Mitsutoshi
Ishii, Hideki
Murohara, Toyoaki
Prognostic Importance of Multiple Nutrition Screening Indexes for 1-Year Mortality in Hospitalized Acute Decompensated Heart Failure Patients
title Prognostic Importance of Multiple Nutrition Screening Indexes for 1-Year Mortality in Hospitalized Acute Decompensated Heart Failure Patients
title_full Prognostic Importance of Multiple Nutrition Screening Indexes for 1-Year Mortality in Hospitalized Acute Decompensated Heart Failure Patients
title_fullStr Prognostic Importance of Multiple Nutrition Screening Indexes for 1-Year Mortality in Hospitalized Acute Decompensated Heart Failure Patients
title_full_unstemmed Prognostic Importance of Multiple Nutrition Screening Indexes for 1-Year Mortality in Hospitalized Acute Decompensated Heart Failure Patients
title_short Prognostic Importance of Multiple Nutrition Screening Indexes for 1-Year Mortality in Hospitalized Acute Decompensated Heart Failure Patients
title_sort prognostic importance of multiple nutrition screening indexes for 1-year mortality in hospitalized acute decompensated heart failure patients
topic Original article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890280/
https://www.ncbi.nlm.nih.gov/pubmed/33693118
http://dx.doi.org/10.1253/circrep.CR-18-0018
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