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Post‐traumatic cerebral fat embolism syndrome with a favourable outcome: a case report
BACKGROUND: Fat embolism syndrome (FES) is a change in physiology resulting from mechanical causes, trauma, or sepsis. Neurological manifestations of FES can vary from mild cognitive changes to coma and even cerebral oedema and brain death. Here, we present an unusual case of cerebral fat emboli tha...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890386/ https://www.ncbi.nlm.nih.gov/pubmed/33602171 http://dx.doi.org/10.1186/s12883-021-02076-0 |
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author | Wang, Wei Chen, Weibi Zhang, Yan Su, Yingying Wang, Yuping |
author_facet | Wang, Wei Chen, Weibi Zhang, Yan Su, Yingying Wang, Yuping |
author_sort | Wang, Wei |
collection | PubMed |
description | BACKGROUND: Fat embolism syndrome (FES) is a change in physiology resulting from mechanical causes, trauma, or sepsis. Neurological manifestations of FES can vary from mild cognitive changes to coma and even cerebral oedema and brain death. Here, we present an unusual case of cerebral fat emboli that occurred in the absence of acute chest syndrome or right-to-left shunt. CASE PRESENTATION: A previously healthy 57-year-old right-handed male was admitted to our department because of unconsciousness after a car accident for 3 days. He suffered from multiple fractures of the bilateral lower extremities and pelvis. This patient had severe anaemia and thrombocytopenia. Head MRI showed multiple small lesions in the whole brain consistent with a “star field” pattern, including high signals on T2-weighted (T2w) and fluid-attenuated inversion recovery (FLAIR) images in the bilateral centrum semiovale; both frontal, parietal and occipital lobes; and brainstem, cerebellar hemisphere, and deep and subcortical white matter. Intravenous methylprednisolone, heparin, mannitol, antibiotics and nutritional support were used. Although this patient had severe symptoms at first, the outcome was favourable. CONCLUSIONS: When patients have long bone and pelvic fractures, multiple bone fractures and deteriorated neurological status, cerebral fat embolism (CFE) should be considered. Additionally, CFE may occur without an intracardiac shunt. The early diagnosis and appropriate management of FES are important, and prior to and following surgery, patients should be monitored comprehensively in the intensive care unit. With appropriate treatment, CFE patients may achieve good results. |
format | Online Article Text |
id | pubmed-7890386 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-78903862021-02-18 Post‐traumatic cerebral fat embolism syndrome with a favourable outcome: a case report Wang, Wei Chen, Weibi Zhang, Yan Su, Yingying Wang, Yuping BMC Neurol Case Report BACKGROUND: Fat embolism syndrome (FES) is a change in physiology resulting from mechanical causes, trauma, or sepsis. Neurological manifestations of FES can vary from mild cognitive changes to coma and even cerebral oedema and brain death. Here, we present an unusual case of cerebral fat emboli that occurred in the absence of acute chest syndrome or right-to-left shunt. CASE PRESENTATION: A previously healthy 57-year-old right-handed male was admitted to our department because of unconsciousness after a car accident for 3 days. He suffered from multiple fractures of the bilateral lower extremities and pelvis. This patient had severe anaemia and thrombocytopenia. Head MRI showed multiple small lesions in the whole brain consistent with a “star field” pattern, including high signals on T2-weighted (T2w) and fluid-attenuated inversion recovery (FLAIR) images in the bilateral centrum semiovale; both frontal, parietal and occipital lobes; and brainstem, cerebellar hemisphere, and deep and subcortical white matter. Intravenous methylprednisolone, heparin, mannitol, antibiotics and nutritional support were used. Although this patient had severe symptoms at first, the outcome was favourable. CONCLUSIONS: When patients have long bone and pelvic fractures, multiple bone fractures and deteriorated neurological status, cerebral fat embolism (CFE) should be considered. Additionally, CFE may occur without an intracardiac shunt. The early diagnosis and appropriate management of FES are important, and prior to and following surgery, patients should be monitored comprehensively in the intensive care unit. With appropriate treatment, CFE patients may achieve good results. BioMed Central 2021-02-18 /pmc/articles/PMC7890386/ /pubmed/33602171 http://dx.doi.org/10.1186/s12883-021-02076-0 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Wang, Wei Chen, Weibi Zhang, Yan Su, Yingying Wang, Yuping Post‐traumatic cerebral fat embolism syndrome with a favourable outcome: a case report |
title | Post‐traumatic cerebral fat embolism syndrome with a favourable outcome: a case report |
title_full | Post‐traumatic cerebral fat embolism syndrome with a favourable outcome: a case report |
title_fullStr | Post‐traumatic cerebral fat embolism syndrome with a favourable outcome: a case report |
title_full_unstemmed | Post‐traumatic cerebral fat embolism syndrome with a favourable outcome: a case report |
title_short | Post‐traumatic cerebral fat embolism syndrome with a favourable outcome: a case report |
title_sort | post‐traumatic cerebral fat embolism syndrome with a favourable outcome: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890386/ https://www.ncbi.nlm.nih.gov/pubmed/33602171 http://dx.doi.org/10.1186/s12883-021-02076-0 |
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