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Accumbens Cholinergic Interneurons Mediate Cue-Induced Nicotine Seeking and Associated Glutamatergic Plasticity

Nicotine, the primary addictive substance in tobacco, is widely abused. Relapse to cues associated with nicotine results in increased glutamate release within nucleus accumbens core (NAcore), modifying synaptic plasticity of medium spiny neurons (MSNs), which contributes to reinstatement of nicotine...

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Detalles Bibliográficos
Autores principales: Leyrer-Jackson, Jonna M., Holter, Michael, Overby, Paula F., Newbern, Jason M., Scofield, Michael D., Olive, M. Foster, Gipson, Cassandra D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890519/
https://www.ncbi.nlm.nih.gov/pubmed/33239269
http://dx.doi.org/10.1523/ENEURO.0276-20.2020