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Extracellular vesicles derived from macrophages display glycyl‐tRNA synthetase 1 and exhibit anti‐cancer activity
Glycyl‐tRNA synthetase 1 (GARS1), a cytosolic enzyme secreted from macrophages, promotes apoptosis in cancer cells. However, the mechanism underlying GARS1 secretion has not been elucidated. Here, we report that GARS1 is secreted through unique extracellular vesicles (EVs) with a hydrodynamic diamet...
Autores principales: | Goughnour, Peter C., Park, Min Chul, Kim, Sang Bum, Jun, Sangmi, Yang, Won Suk, Chae, Sehyun, Cho, Seongmin, Song, Chihong, Lee, Ji‐Hyun, Hyun, Jae Kyung, Kim, Byung Gyu, Hwang, Daehee, Jung, Hyun Suk, Gho, Yong Song, Kim, Sunghoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890555/ https://www.ncbi.nlm.nih.gov/pubmed/33708357 http://dx.doi.org/10.1002/jev2.12029 |
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