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Oligosaccharides increase the genotoxic effect of colibactin produced by pks+ Escherichia coli strains
BACKGROUND: Colibactin is a genotoxin that induces DNA double-strand breaks that may lead to carcinogenesis and is produced by Escherichia coli strains harboring the pks island. Human and animal studies have shown that colibactin-producing gut bacteria promote carcinogenesis and enhance the progress...
Autores principales: | Oliero, Manon, Calvé, Annie, Fragoso, Gabriela, Cuisiniere, Thibault, Hajjar, Roy, Dobrindt, Ulrich, Santos, Manuela M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890614/ https://www.ncbi.nlm.nih.gov/pubmed/33596864 http://dx.doi.org/10.1186/s12885-021-07876-8 |
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