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Platelets and lymphocytes drive progressive penumbral tissue loss during middle cerebral artery occlusion in mice

BACKGROUND: In acute ischemic stroke, cessation of blood flow causes immediate tissue necrosis within the center of the ischemic brain region accompanied by functional failure in the surrounding brain tissue designated the penumbra. The penumbra can be salvaged by timely thrombolysis/thrombectomy, t...

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Detalles Bibliográficos
Autores principales:	Schuhmann, Michael K., Bieber, Michael, Franke, Maximilian, Kollikowski, Alexander M., Stegner, David, Heinze, Katrin G., Nieswandt, Bernhard, Pham, Mirko, Stoll, Guido
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890632/ https://www.ncbi.nlm.nih.gov/pubmed/33602266 http://dx.doi.org/10.1186/s12974-021-02095-1

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