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Cross-species examination of X-chromosome inactivation highlights domains of escape from silencing

BACKGROUND: X-chromosome inactivation (XCI) in eutherian mammals is the epigenetic inactivation of one of the two X chromosomes in XX females in order to compensate for dosage differences with XY males. Not all genes are inactivated, and the proportion escaping from inactivation varies between human...

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Detalles Bibliográficos
Autores principales:	Balaton, Bradley P., Fornes, Oriol, Wasserman, Wyeth W., Brown, Carolyn J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890635/ https://www.ncbi.nlm.nih.gov/pubmed/33597016 http://dx.doi.org/10.1186/s13072-021-00386-8

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