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Transcriptome profiling of long noncoding RNAs and mRNAs in spinal cord of a rat model of paclitaxel-induced peripheral neuropathy identifies potential mechanisms mediating neuroinflammation and pain
BACKGROUND: Paclitaxel is a widely prescribed chemotherapy drug for treating solid tumors. However, paclitaxel-induced peripheral neuropathy (PIPN) is a common adverse effect during paclitaxel treatment, which results in sensory abnormalities and neuropathic pain among patients. Unfortunately, the m...
Autores principales: | Li, Yuanyuan, Yin, Chengyu, Liu, Boyu, Nie, Huimin, Wang, Jie, Zeng, Danyi, Chen, Ruixiang, He, Xiaofen, Fang, Junfan, Du, Junying, Liang, Yi, Jiang, Yongliang, Fang, Jianqiao, Liu, Boyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890637/ https://www.ncbi.nlm.nih.gov/pubmed/33602238 http://dx.doi.org/10.1186/s12974-021-02098-y |
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