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Medical therapies for postoperative Crohn’s disease

Postoperative recurrence of Crohn’s disease is common and requires a multidisciplinary approach between surgeons and gastroenterologists in the perioperative and postoperative period to improve outcomes in this patient population. Endoscopic recurrence precedes clinical and surgical recurrence and e...

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Detalles Bibliográficos
Autores principales: Shah, Ravi S., Click, Benjamin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890708/
https://www.ncbi.nlm.nih.gov/pubmed/33643440
http://dx.doi.org/10.1177/1756284821993581
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author Shah, Ravi S.
Click, Benjamin H.
author_facet Shah, Ravi S.
Click, Benjamin H.
author_sort Shah, Ravi S.
collection PubMed
description Postoperative recurrence of Crohn’s disease is common and requires a multidisciplinary approach between surgeons and gastroenterologists in the perioperative and postoperative period to improve outcomes in this patient population. Endoscopic recurrence precedes clinical and surgical recurrence and endoscopic monitoring is crucial to guide postoperative management. Risk stratification of patients is recommended to guide early prophylactic management, and follow-up endoscopic monitoring can guide intensification of therapy. This review summarizes evidence behind postoperative recurrence rates, disease monitoring techniques, nonbiologic and biologic therapies available to prevent and treat postoperative recurrence, risk factors associated with recurrence, and postoperative management strategies guided by endoscopic monitoring.
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spelling pubmed-78907082021-02-26 Medical therapies for postoperative Crohn’s disease Shah, Ravi S. Click, Benjamin H. Therap Adv Gastroenterol Review Postoperative recurrence of Crohn’s disease is common and requires a multidisciplinary approach between surgeons and gastroenterologists in the perioperative and postoperative period to improve outcomes in this patient population. Endoscopic recurrence precedes clinical and surgical recurrence and endoscopic monitoring is crucial to guide postoperative management. Risk stratification of patients is recommended to guide early prophylactic management, and follow-up endoscopic monitoring can guide intensification of therapy. This review summarizes evidence behind postoperative recurrence rates, disease monitoring techniques, nonbiologic and biologic therapies available to prevent and treat postoperative recurrence, risk factors associated with recurrence, and postoperative management strategies guided by endoscopic monitoring. SAGE Publications 2021-02-15 /pmc/articles/PMC7890708/ /pubmed/33643440 http://dx.doi.org/10.1177/1756284821993581 Text en © The Author(s), 2021 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Shah, Ravi S.
Click, Benjamin H.
Medical therapies for postoperative Crohn’s disease
title Medical therapies for postoperative Crohn’s disease
title_full Medical therapies for postoperative Crohn’s disease
title_fullStr Medical therapies for postoperative Crohn’s disease
title_full_unstemmed Medical therapies for postoperative Crohn’s disease
title_short Medical therapies for postoperative Crohn’s disease
title_sort medical therapies for postoperative crohn’s disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890708/
https://www.ncbi.nlm.nih.gov/pubmed/33643440
http://dx.doi.org/10.1177/1756284821993581
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