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Differential SOD2 and GSTZ1 profiles contribute to contrasting dental pulp stem cell susceptibilities to oxidative damage and premature senescence

BACKGROUND: Dental pulp stem cells (DPSCs) are increasingly being advocated as viable cell sources for regenerative medicine-based therapies. However, significant heterogeneity in DPSC expansion and multi-potency capabilities are well-established, attributed to contrasting telomere profiles and susc...

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Detalles Bibliográficos
Autores principales: Alaidaroos, Nadia Y. A., Alraies, Amr, Waddington, Rachel J., Sloan, Alastair J., Moseley, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890809/
https://www.ncbi.nlm.nih.gov/pubmed/33596998
http://dx.doi.org/10.1186/s13287-021-02209-9