Down-regulation of the tumor suppressor miR-34a contributes to head and neck cancer by up-regulating the MET oncogene and modulating tumor immune evasion

BACKGROUND: MicroRNAs (miRs) have been shown to play an important role in tumorigenesis, including in head and neck squamous cell carcinoma (HNSCC). The miR-34 family is thought to play a role in tumor suppression, but the exact mechanism of their action in HNSCC is not well understood. Moreover, th...

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Detalles Bibliográficos
Autores principales: Wu, Xun, Cheng, Yi-Shing Lisa, Matthen, Mathew, Yoon, Angela, Schwartz, Gary K., Bala, Shashi, Taylor, Alison M., Momen-Heravi, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890893/
https://www.ncbi.nlm.nih.gov/pubmed/33596979
http://dx.doi.org/10.1186/s13046-021-01865-2

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