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Turning off the alarm – Targeting alarmins and other epithelial mediators of allergic inflammation with biologics
Besides the major players IL-4, IL-13, IL-5, and IgE as targets for biologics, other mediators have been identified that are secreted by epithelial cells and act upstream in the cascade of allergic inflammation. Such are the alarmin IL-33 as well as TSLP and IL-5. The role of each cytokine in sensit...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dustri-Verlag Dr. Karl Feistle
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890934/ https://www.ncbi.nlm.nih.gov/pubmed/33615121 http://dx.doi.org/10.5414/ALX02194E |