Preliminary, Real-world, Multicenter Experience With Omadacycline for Mycobacterium abscessus Infections

Twelve patients were treated with omadacycline (OMC) as part of a multidrug regimen for Mycobacterium abscessus. The majority of infections were of pulmonary origin (7/12; 58.3%). The median (interquartile range) duration of OMC was 6.2 (4.2–11.0) months. Clinical success occurred in 9/12 (75.0%) pa...

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Autores principales: Morrisette, Taylor, Alosaimy, Sara, Philley, Julie V, Wadle, Carly, Howard, Catessa, Webb, Andrew J, Veve, Michael P, Barger, Melissa L, Bouchard, Jeannette, Gore, Tristan W, Lagnf, Abdalhamid M, Ansari, Iman, Mejia-Chew, Carlos, Cohen, Keira A, Rybak, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890947/
https://www.ncbi.nlm.nih.gov/pubmed/33628856
http://dx.doi.org/10.1093/ofid/ofab002
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author Morrisette, Taylor
Alosaimy, Sara
Philley, Julie V
Wadle, Carly
Howard, Catessa
Webb, Andrew J
Veve, Michael P
Barger, Melissa L
Bouchard, Jeannette
Gore, Tristan W
Lagnf, Abdalhamid M
Ansari, Iman
Mejia-Chew, Carlos
Cohen, Keira A
Rybak, Michael J
author_facet Morrisette, Taylor
Alosaimy, Sara
Philley, Julie V
Wadle, Carly
Howard, Catessa
Webb, Andrew J
Veve, Michael P
Barger, Melissa L
Bouchard, Jeannette
Gore, Tristan W
Lagnf, Abdalhamid M
Ansari, Iman
Mejia-Chew, Carlos
Cohen, Keira A
Rybak, Michael J
author_sort Morrisette, Taylor
collection PubMed
description Twelve patients were treated with omadacycline (OMC) as part of a multidrug regimen for Mycobacterium abscessus. The majority of infections were of pulmonary origin (7/12; 58.3%). The median (interquartile range) duration of OMC was 6.2 (4.2–11.0) months. Clinical success occurred in 9/12 (75.0%) patients. Three patients experienced a possible adverse effect while on therapy.
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spelling pubmed-78909472021-02-23 Preliminary, Real-world, Multicenter Experience With Omadacycline for Mycobacterium abscessus Infections Morrisette, Taylor Alosaimy, Sara Philley, Julie V Wadle, Carly Howard, Catessa Webb, Andrew J Veve, Michael P Barger, Melissa L Bouchard, Jeannette Gore, Tristan W Lagnf, Abdalhamid M Ansari, Iman Mejia-Chew, Carlos Cohen, Keira A Rybak, Michael J Open Forum Infect Dis Brief Reports Twelve patients were treated with omadacycline (OMC) as part of a multidrug regimen for Mycobacterium abscessus. The majority of infections were of pulmonary origin (7/12; 58.3%). The median (interquartile range) duration of OMC was 6.2 (4.2–11.0) months. Clinical success occurred in 9/12 (75.0%) patients. Three patients experienced a possible adverse effect while on therapy. Oxford University Press 2021-01-07 /pmc/articles/PMC7890947/ /pubmed/33628856 http://dx.doi.org/10.1093/ofid/ofab002 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Morrisette, Taylor
Alosaimy, Sara
Philley, Julie V
Wadle, Carly
Howard, Catessa
Webb, Andrew J
Veve, Michael P
Barger, Melissa L
Bouchard, Jeannette
Gore, Tristan W
Lagnf, Abdalhamid M
Ansari, Iman
Mejia-Chew, Carlos
Cohen, Keira A
Rybak, Michael J
Preliminary, Real-world, Multicenter Experience With Omadacycline for Mycobacterium abscessus Infections
title Preliminary, Real-world, Multicenter Experience With Omadacycline for Mycobacterium abscessus Infections
title_full Preliminary, Real-world, Multicenter Experience With Omadacycline for Mycobacterium abscessus Infections
title_fullStr Preliminary, Real-world, Multicenter Experience With Omadacycline for Mycobacterium abscessus Infections
title_full_unstemmed Preliminary, Real-world, Multicenter Experience With Omadacycline for Mycobacterium abscessus Infections
title_short Preliminary, Real-world, Multicenter Experience With Omadacycline for Mycobacterium abscessus Infections
title_sort preliminary, real-world, multicenter experience with omadacycline for mycobacterium abscessus infections
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890947/
https://www.ncbi.nlm.nih.gov/pubmed/33628856
http://dx.doi.org/10.1093/ofid/ofab002
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