Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets

Nonhuman primate (NHP) models will expedite therapeutics and vaccines for COVID-19 into clinical trials. We compared acute SARS-CoV-2 infection in young and old rhesus macaques and baboons and old marmosets. Macaques had clinical signs of viral infection, mild-to-moderate pneumonitis and extra-pulmo...

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Autores principales: Singh, Dhiraj Kumar, Singh, Bindu, Ganatra, Shashank R., Gazi, Michal, Cole, Journey, Thippeshappa, Rajesh, Alfson, Kendra J., Clemmons, Elizabeth, Gonzalez, Olga, Escobedo, Ruby, Lee, Tae-Hyung, Chatterjee, Ayan, Goez-Gazi, Yenny, Sharan, Riti, Gough, Maya, Alvarez, Cynthia, Blakley, Alyssa, Ferdin, Justin, Bartley, Carmen, Staples, Hilary, Parodi, Laura, Callery, Jessica, Mannino, Amanda, Klaffke, Benjamin, Escareno, Priscilla, Platt, Roy N., Hodara, Vida, Scordo, Julia, Gautam, Shalini, Vilanova, Andreu G., Olmo-Fontanez, Angelica, Schami, Alyssa, Oyejide, Adelekan, Ajithdoss, Dharani K., Copin, Richard, Baum, Alina, Kyratsous, Christos, Alvarez, Xavier, Ahmed, Mushtaq, Rosa, Bruce, Goodroe, Anna, Dutton, John, Hall-Ursone, Shannan, Frost, Patrice A., Voges, Andra K., Ross, Corinna N., Sayers, Ken, Chen, Christopher, Hallam, Cory, Khader, Shabaana A., Mitreva, Makedonka, Anderson, Timothy J. C., Martinez-Sobrido, Luis, Patterson, Jean L., Turner, Joanne, Torrelles, Jordi B., Dick, Edward J., Brasky, Kathleen, Schlesinger, Larry S., Giavedoni, Luis D., Carrion, Ricardo, Kaushal, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890948/
https://www.ncbi.nlm.nih.gov/pubmed/33340034
http://dx.doi.org/10.1038/s41564-020-00841-4

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