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Immunostimulatory siRNA with a uridine bulge leads to potent inhibition of HBV and activation of innate immunity

BACKGROUND: Hepatitis B virus (HBV) infection is difficult to cure. HBV-specific immune tolerance plays a key role in HBV persistence, and enhancing cellular and humoral immunity will improve the control of HBV infection. The purpose of the study was to explore the anti-HBV and immunostimulatory eff...

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Detalles Bibliográficos
Autores principales:	Lan, Tingyu, Wei, Zhiqiang, He, Yulin, Wan, Song, Liu, Li, Cheng, Bin, Li, Ruimin, Chen, Hongxia, Liu, Guohua, Meng, Zhongji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890953/ https://www.ncbi.nlm.nih.gov/pubmed/33602251 http://dx.doi.org/10.1186/s12985-021-01509-z

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