The FAM3C locus that encodes interleukin-like EMT inducer (ILEI) is frequently co-amplified in MET-amplified cancers and contributes to invasiveness

BACKGROUND: Gene amplification of MET, which encodes for the receptor tyrosine kinase c-MET, occurs in a variety of human cancers. High c-MET levels often correlate with poor cancer prognosis. Interleukin-like EMT inducer (ILEI) is also overexpressed in many cancers and is associated with metastasis...

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Detalles Bibliográficos
Autores principales: Schmidt, Ulrike, Heller, Gerwin, Timelthaler, Gerald, Heffeter, Petra, Somodi, Zsolt, Schweifer, Norbert, Sibilia, Maria, Berger, Walter, Csiszar, Agnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890988/
https://www.ncbi.nlm.nih.gov/pubmed/33596971
http://dx.doi.org/10.1186/s13046-021-01862-5

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