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Monitoring and forecasting the COVID-19 epidemic in the UK

This paper shows how existing methods of time series analysis and modeling can be exploited in novel ways to monitor and forecast the COVID-19 epidemic. In the past, epidemics have been monitored by various statistical and model metrics, such as evaluation of the effective reproduction number, [Form...

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Autores principales: Young, Peter C., Chen, Fengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891108/
https://www.ncbi.nlm.nih.gov/pubmed/33623480
http://dx.doi.org/10.1016/j.arcontrol.2021.01.004
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author Young, Peter C.
Chen, Fengwei
author_facet Young, Peter C.
Chen, Fengwei
author_sort Young, Peter C.
collection PubMed
description This paper shows how existing methods of time series analysis and modeling can be exploited in novel ways to monitor and forecast the COVID-19 epidemic. In the past, epidemics have been monitored by various statistical and model metrics, such as evaluation of the effective reproduction number, [Formula: see text]. However, [Formula: see text] can be difficult and time consuming to compute. This paper suggests two relatively simple data-based metrics that could be used in conjunction with [Formula: see text] estimation and provide rapid indicators of how the epidemic’s dynamic behavior is progressing. The new metrics are the epidemic rate of change (RC) and a related state-dependent response rate parameter (RP), recursive estimates of which are obtained from dynamic harmonic and dynamic linear regression (DHR and DLR) algorithms. Their effectiveness is illustrated by the analysis of COVID-19 data in the UK and Italy. The paper also shows how similar methodology, combined with the refined instrumental variable method for estimating hybrid Box–Jenkins models of linear dynamic systems (RIVC), can be used to relate the daily death numbers in the Italian and UK epidemics and then provide 15-day-ahead forecasts of the UK daily death numbers. The same approach can be used to model and forecast the UK epidemic based on the daily number of COVID-19 patients in UK hospitals. Finally, the paper speculates on how the state-dependent parameter (SDP) modeling procedures may provide data-based insight into a nonlinear differential equation model for epidemics such as COVID-19.
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spelling pubmed-78911082021-02-19 Monitoring and forecasting the COVID-19 epidemic in the UK Young, Peter C. Chen, Fengwei Annu Rev Control Article This paper shows how existing methods of time series analysis and modeling can be exploited in novel ways to monitor and forecast the COVID-19 epidemic. In the past, epidemics have been monitored by various statistical and model metrics, such as evaluation of the effective reproduction number, [Formula: see text]. However, [Formula: see text] can be difficult and time consuming to compute. This paper suggests two relatively simple data-based metrics that could be used in conjunction with [Formula: see text] estimation and provide rapid indicators of how the epidemic’s dynamic behavior is progressing. The new metrics are the epidemic rate of change (RC) and a related state-dependent response rate parameter (RP), recursive estimates of which are obtained from dynamic harmonic and dynamic linear regression (DHR and DLR) algorithms. Their effectiveness is illustrated by the analysis of COVID-19 data in the UK and Italy. The paper also shows how similar methodology, combined with the refined instrumental variable method for estimating hybrid Box–Jenkins models of linear dynamic systems (RIVC), can be used to relate the daily death numbers in the Italian and UK epidemics and then provide 15-day-ahead forecasts of the UK daily death numbers. The same approach can be used to model and forecast the UK epidemic based on the daily number of COVID-19 patients in UK hospitals. Finally, the paper speculates on how the state-dependent parameter (SDP) modeling procedures may provide data-based insight into a nonlinear differential equation model for epidemics such as COVID-19. Published by Elsevier Ltd. 2021 2021-02-18 /pmc/articles/PMC7891108/ /pubmed/33623480 http://dx.doi.org/10.1016/j.arcontrol.2021.01.004 Text en Crown Copyright © 2021 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Young, Peter C.
Chen, Fengwei
Monitoring and forecasting the COVID-19 epidemic in the UK
title Monitoring and forecasting the COVID-19 epidemic in the UK
title_full Monitoring and forecasting the COVID-19 epidemic in the UK
title_fullStr Monitoring and forecasting the COVID-19 epidemic in the UK
title_full_unstemmed Monitoring and forecasting the COVID-19 epidemic in the UK
title_short Monitoring and forecasting the COVID-19 epidemic in the UK
title_sort monitoring and forecasting the covid-19 epidemic in the uk
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891108/
https://www.ncbi.nlm.nih.gov/pubmed/33623480
http://dx.doi.org/10.1016/j.arcontrol.2021.01.004
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